The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

28 articles for Z Jin


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor.EBI
The Scripps Research Institute
Synthesis and activity of substituted heteroaromatics as positive allosteric modulators fora4ß2a5 nicotinic acetylcholine receptors.EBI
The Scripps Research Institute
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.EBI
Tufts University Sackler School of Biomedical Sciences
Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety.EBI
Tufts University
Anti-influenza virus activities and mechanism of antrafenine analogs.EBI
The Chinese University of Hong Kong
Discovery and Optimization of Hsp110 and sGC Dual-Target Regulators for the Treatment of Pulmonary Arterial Hypertension.EBI
Central South University
N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors.EBI
Methylgene
Discovery of Novel Oxazepine Derivatives as Akt/ROCK Inhibitors for Growth Arrest and Differentiation Induction in Neuroblastoma Treatment.EBI
Zhejiang University
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against EBI
University of Ljubljana
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate EBI
University of Ljubljana
Discovery of novel ataxia telangiectasia mutated (ATM) kinase modulators: Computational simulation, biological evaluation and cancer combinational chemotherapy study.EBI
Peking University
Optimization of 4-arylthiophene-3-carboxylic acid derivatives as inhibitors of ANO1: Lead optimization studies toward their analgesic efficacy for inflammatory pain.EBI
Peking University
Design, synthesis and biological activities of benzo[d]imidazo[1,2-a]imidazole derivatives as TRPM2-specfic inhibitors.EBI
Peking University
The Discovery of Novel ACA Derivatives as Specific TRPM2 Inhibitors that Reduce Ischemic Injury Both In Vitro and In Vivo.EBI
Peking University
Discovery of EBI
Zhejiang University
Design, synthesis and biological evaluation of novel pleuromutilin derivatives as potent anti-MRSA agents targeting the 50S ribosome.EBI
South China Agricultural University
Design, synthesis and biological activities of novel pleuromutilin derivatives with a substituted triazole moiety as potent antibacterial agents.EBI
South China Agricultural University
A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.EBI
University of Copenhagen
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of EBI
Janssen Biopharma
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design.EBI
Chinese Academy of Sciences
Synthesis and Anti-HCV Activities of 4'-Fluoro-2'-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4'-Fluoro-2'- C-methyluridine 5'-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection.EBI
Janssen Biopharma
Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.EBI
University of Michigan
Heteroaromatic amide derivative and medicament containing the sameBDB
Kaken Pharmaceutical Co.
PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOFBDB
Hansoh Bio
Factor XIa inhibitorsBDB
Merck Sharp & Dohme
Highly selective sigma receptor radioligandsBDB
The University of Mississippi
Synthesis and characterization of azole isoflavone inhibitors of aromatase.BDB
Ohio State University
Inhibition of human caspases by peptide-based and macromolecular inhibitors.BDB
Merck Research Laboratories