BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 778K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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23 articles for RF Bruns

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
50
N6-substituted adenosine receptor agonists: potential antihypertensive agents.EBI
Warner-Lambert
43
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.EBI
Warner-Lambert
9
N6-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor.EBI
Warner-Lambert
19
N6-[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]adenosine and its uronamide derivatives. Novel adenosine agonists with both high affinity and high selectivity for the adenosine A2 receptor.EBI
Warner-Lambert
16
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor.EBI
Warner-Lambert
16
N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity.EBI
Parke-Davis Pharmaceutical Research Division
18
Ribose-modified adenosine analogues as adenosine receptor agonists.EBI
TBA
77
Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application.EBI
TBA
13
N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists.EBI
TBA
10
 
Diphenylpyrazolidinone and benzodiazepine cholecystokinin antagonists: A case of convergent evolution in medicinal chemistryEBI
TBA
78
Azetidinones as vasopressin V1a antagonists.EBI
Lehigh University
20
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists.EBI
Eli Lilly
49
Structure-activity relationships of a series of benzothiophene-derived NPY Y1 antagonists: optimization of the C-2 side chain.EBI
Eli Lilly
19
Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists.EBI
Eli Lilly
28
Synthesis and evaluation of a series of novel 2-[(4-chlorophenoxy)methyl]benzimidazoles as selective neuropeptide Y Y1 receptor antagonists.EBI
Eli Lilly
3
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1EBI
AMRI
12
Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists.EBI
Eli Lilly
54
3-Aryl-1,2-diacetamidopropane derivatives as novel and potent NK-1 receptor antagonists.EBI
Eli Lilly
15
[1,2,4]Triazolo[4,3-a]quinoxalin-4-amines: a new class of A1 receptor selective adenosine antagonists.EBI
Warner-Lambert
22
Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.EBI
University of South Florida
1
Evaluation and synthesis of aminohydroxyisoxazoles and pyrazoles as potential glycine agonists.EBI
Warner-Lambert
12
Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.EBI
Warner-Lambert
21
Discovery of Boronic Acids as Novel and Potent Inhibitors of Fatty Acid Amide Hydrolase.BDB
University of Oxford