Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

8 articles for JE Leysen

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.

Janssen Research Foundation

Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor.

Vu University Medical Center

Inhibitors of IRAK4 activity

Merck Sharp & Dohme

Oxazoline and isoxazoline derivatives as CRAC modulators

Lupin

Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain.

Stanford University

Biarylether amide quinolines as liver X receptor agonists.

Wyeth Research

N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.

Bristol-Myers Squibb

Novel tricyclic inhibitors of IkappaB kinase.

Bristol-Myers Squibb