BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

13 articles for K Appelt

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease.EBI
Agouron Pharmaceuticals
 
Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitorsEBI
TBA
 
Isophthalic acid derivatives: amino acid surrogates for the inhibition of HIV-1 proteaseEBI
TBA
 
A systematic study of P1–P3 spanning sidechains for the inhibition of HIV-1 proteaseEBI
TBA
Structure-based design, synthesis, and antimicrobial activity of indazole-derived SAH/MTA nucleosidase inhibitors.EBI
Quorex Pharmaceuticals
Calculation of relative differences in the binding free energies of HIV1 protease inhibitors: a thermodynamic cycle perturbation approach.EBI
Agouron Pharmaceuticals
Design of enzyme inhibitors using iterative protein crystallographic analysis.EBI
Agouron Pharmaceuticals
Indazoles and use thereofBDB
Purdue Pharma
Tetrazole derivatives and their use as potassium channel modulatorsBDB
Saniona
Kinase modulating compounds, compositions containing the same and use thereofBDB
Centaurus Biopharma
Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivativesBDB
Duke University
Methods for the treatment of locally advanced breast cancerBDB
Celgene
Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines.BDB
Sapienza University of Rome