BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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24 articles for M Tintelnot-Blomley

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors.EBI
Novartis Institutes For Biomedical Research
Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor.EBI
Novartis Institutes For Biomedical Research
Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors.EBI
University of Montreal
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application.EBI
Novartis Institutes For Biomedical Research
Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo.EBI
Novartis Institutes For Biomedical Research
 
Novel pseudosymmetric inhibitors of HIV-1 proteaseEBI
TBA
Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360.EBI
TBA
Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer's Disease.EBI
Novartis Pharma
Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K-investigating P1' substituents.EBI
Novartis Pharma
New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development.EBI
Ciba-Geigy
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors.EBI
Novartis Institutes For Biomedical Research
Guanidine derivative and medical use thereofBDB
Toray Industries
Substituted nucleoside derivatives useful as anticancer agentsBDB
Pfizer
Substituted pyridines as inhibitors of human immunodeficiency virus replicationBDB
Viiv Healthcare UK (NO.5)
Inhibitors of lysine specific demethylase-1BDB
Celgene Quanticel Research
Synthesis and biological evaluation of kojic acid derivatives containing 1,2,4-triazole as potent tyrosinase inhibitors.BDB
Hunan University of Science and Technology
Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathwayBDB
Bayer Intellectual Property
Salvinorin derivatives and uses thereofBDB
The Mclean Hospital
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).BDB
Roche Bioscience
Biaryl amide compounds as kinase inhibitorsBDB
Novartis
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.BDB
Astrazeneca
Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors.BDB
Glaxosmithkline