53 articles for Y Lee
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Data
Article Title
Organization
30
Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced into 2-aryl-1,3,4-oxadiazin-5(6H)-one.
Seoul National University
13
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
Seoul National University
25
3-Amino-N-adamantyl-3-methylbutanamide derivatives as 11ß-hydroxysteroid dehydrogenase 1 inhibitor.
Yonsei University
18
Synthesis of quaternarya-amino acid-based arginase inhibitors via the Ugi reaction.
Institutes For Pharmaceutical Discovery
2
Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring.
Yale University
16
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Seoul National University
10
Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.
Yonsei University
15
1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase.
Northwestern University
17
Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A2A and A3 adenosine receptor ligands.
Ewha Womans University
62
Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.
Neurogen
10
X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
Ewha Womans University
24
Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors.
Konkuk University
4
New estrogenic compounds isolated from Broussonetia kazinoki.
Sookmyung Women'S University
3
Structure-Activity Relationship Studies of DNA Methyltransferase 1 Monovalent Degraders.
Icahn School of Medicine at Mount Sinai
1
Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation.
Icahn School Of Medicine At Mount Sinai
3
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.
Cytokinetics Inc
16
Synthesis and biological evaluation of O4'-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents.
Mansoura University
3
Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase.
Ewha Womans University
37
Discovery of N-(1-(2-hydroxyethyl)quinolin-2-one)-N'-(1-phenyl-1H-pyrazol-5-yl)methyl) urea as Mode-Selective TRPV1 antagonist.
Seoul National University
2
Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer.
Icahn School Of Medicine At Mount Sinai
6
Prenylated Chrysin Derivatives as Partial PPARγ Agonists with Adiponectin Secretion-Inducing Activity.
Seoul National University
9
Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors.
University of Arizona
16
Novel allosteric glutaminase 1 inhibitors with macrocyclic structure activity relationship analysis.
Yonsei University College of Medicine
13
Synthesis and insecticidal activity of fluorinated 2-(2,6-dichloro-4-trifluoromethylphenyl)-2,4,5,6-tetrahydrocyclopentapyrazoles.
Johnson & Johnson Pharmaceutical Research and Development
1
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A
University of Southern California
4
Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A
Ewha Womans University
46
Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift.
Seoul National University
3
Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders.
L2 Diagnostics
6
Syntheses of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]-benzothiazolidine derivatives as a potential gastric H+/K(+)-ATPase inhibitor.
Ajou University
4
Adaptable Small Ligand of CYP1 Enzymes for Use in Understanding the Structural Features Determining Isoform Selectivity.
Seoul National University
9
Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists.
Seoul National University
23
Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1.
Ansaris
1
Isolation, Synthesis, and Antisepsis Effects of a C-Methylcoumarinochromone Isolated from Abronia nana Cell Culture.
Kyungpook National University
9
4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase.
University of Kansas
50
SMALL MOLECULE INHIBITION OF DEUBIQUITINATING ENZYME JOSEPHIN DOMAIN CONTAINING 1 (JOSD1) AS A TARGETED THERAPY FOR LEUKEMIAS WITH MUTANT JANUS KINASE 2 (JAK2)
Dana-Farber Cancer Institute
174
PYRAZOLOPYRIDAZINONE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Broadenbio
4
4-Fluoro-Thio-containing inhibitors of APP2, compositions thereof and method of use
TBA
351
Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors
Amgen
27
Expanding the Scope of Human DNA Polymerase ¿ and ß Inhibitors.
University of Konstanz
21
High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations.
Uppsala University
5
Effects of hydroxybenzyl alcohols on melanogenesis in melanocyte-keratinocyte co-culture and monolayer culture of melanocytes.
National Tsing Hua University
5
Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers.
Organon International