8 articles for AD Reith
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor.
Glaxosmithkline
The identification of potent and selective imidazole-based inhibitors of B-Raf kinase.
Glaxosmithkline
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
University of Dundee
Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors.
Gsk Pharmaceuticals R&D
5-Substituted-N-pyridazinylbenzamides as potent and selective LRRK2 inhibitors: Improved brain unbound fraction enables efficacy.
Gsk Pharmaceuticals R&D
Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors.
Neurodegeneration Dpu
Substituted piperidine compounds and their use as orexin receptor modulators
Janssen Pharmaceutica