30 articles for E Oldfield
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
University of Illinois At Urbana-Champaign
Multitarget drug discovery for tuberculosis and other infectious diseases.
University of Illinois At Urbana-Champaign
A quantitative structure-activity relationship and pharmacophore modeling investigation of aryl-X and heterocyclic bisphosphonates as bone resorption agents.
University of Illinois At Urbana-Champaign
HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
TBA
Head-to-head prenyl tranferases: anti-infective drug targets.
University of Illinois At Urbana-Champaign
Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies.
Instituto Venezolano De Investigaciones Cient£Ficas
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Institute of Biological Chemistry
Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase.
University of Illinois At Urbana-Champaign
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
University of Illinois At Urbana-Champaign
Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.
National Institute of Immunology
Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.
University of Illinois At Urbana-Champaign
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
University of Illinois At Urbana-Champaign
Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation.
University of Illinois At Urbana-Champaign
Activity of sulfonium bisphosphonates on tumor cell lines.
University of Illinois At Urbana-Champaign
Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria.
University of Illinois At Urbana-Champaign
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.
Instituto Venezolano De Investigaciones CientíFicas
Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.
University of Illinois At Urbana-Champaign
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
University of Illinois At Urbana-Champaign
3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates.
University of Illinois At Urbana-Champaign
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents.
University of Illinois At Urbana-Champaign
Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis.
Chinese Academy of Sciences
Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells.
Tsinghua University
Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms.
University of Illinois At Urbana-Champaign
Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin.
University of Illinois At Urbana - Champaign
Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA).
Al-Azhar University
Pharmaceutical compositions comprising RET inhibitors and methods for the treatment of cancer
Queen'S University At Kingston
Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.
Mcgill University
3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds
Hoffmann-La Roche