66 articles for M Jung
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Anti-inflammatory tetraquinane diterpenoids from a Crinipellis species.
University of Kaiserslautern
Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis.
Martin-Luther University of Halle-Wittenberg
KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases.
University of Freiburg
Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study.
Albert-Ludwigs-University of Freiburg
Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors.
Albert-Ludwigs-University of Freiburg
Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site.
TBA
Nonpeptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity.
University of Freiburg
Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.
Sapienza University of Rome
Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).
Ludwig-Maximilians-Universit£T M£Nchen
Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).
University of Freiburg
Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.
Albert-Ludwigs-University of Freiburg
Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.
Yonsei University
A novel arginine methyltransferase inhibitor with cellular activity.
Albert-Ludwigs-University of Freiburg
Target-based approach to inhibitors of histone arginine methyltransferases.
Albert-Ludwigs-University of Freiburg
Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.
Albert-Ludwigs-University of Freiburg
Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors.
Albert-Ludwigs-University of Freiburg
Computer- and structure-based lead design for epigenetic targets.
Martin-Luther University of Halle-Wittenberg
Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins).
Ernst-Moritz-Arndt University Greifswald
Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).
University of East Anglia
The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
Georgetown University Medical Center
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
Icahn School of Medicine At Mount Sinai
Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD+-Dependent Lysine Deacylase Sirtuin 2.
University of Freiburg
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
Leipzig University
A novel pan-selective bromodomain inhibitor for epigenetic drug design.
Albert-Ludwigs-Universit£T Freiburg
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
Albert-Ludwigs-University of Freiburg
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
University of Siena
Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Martin-Luther University of Halle-Wittenberg
Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.
Ludwig-Maximilians University
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
University of Siena
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Martin-Luther University of Halle-Wittenberg
Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
Ludwig-Maximilians University
Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
Martin-Luther University of Halle-Wittenberg
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
University of Siena
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation.
University of Siena
4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines.
Albert-Ludwigs-Universit£T Freiburg
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells.
WestfäLische Wilhelms-UniversitäT MüNster
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease.
University of Bras£Lia
Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation.
WestfäLische Wilhelms-UniversitäT MüNster
Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).
Icahn School of Medicine At Mount Sinai
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
Ludwig-Maximilians University Munich
Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6.
University of Pennsylvania
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
University of Oxford
Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from
University of Freiburg
The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors.
Imperial College London
Novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice.
Georgetown University Medical Center
Subtype selective substrates for histone deacetylases.
Westf£Lische Wilhelms-Universit£T M£Nster
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.
TBA
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.
University of Siena
Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.
University of Freiburg
Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).
University of Freiburg
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
University of Strasbourg
Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity.
Martin-Luther University of Halle-Wittenberg
Alkoxyurea-Based Histone Deacetylase Inhibitors Increase Cisplatin Potency in Chemoresistant Cancer Cell Lines.
Heinrich-Heine-Universit£T D£Sseldorf
Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.
Heinrich-Heine-Universit£T D£Sseldorf
6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use
Purdue Research Foundation
Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity
Neuraxon