BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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8 articles for B Fisher

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.EBI
Amgen
Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development.EBI
Amgen
Inhibiting NF-¿B-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures.EBI
Amgen
Discovery and optimization of a series of liver X receptor antagonists.EBI
Amgen
Discovery of a new binding mode for a series of liver X receptor agonists.EBI
Amgen
Discovery of a Highly Selective STK16 Kinase Inhibitor.BDB
Chinese Academy of Sciences
Inhibition of arginine aminopeptidase by bestatin and arphamenine analogues. Evidence for a new mode of binding to aminopeptidases.BDB
University of Wisconsin
Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB.BDB
Leiden University