35 articles for Y Choi
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
N-Arylsulfonyl-a-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity.
Boehringer Ingelheim Pharmaceuticals
Structure-activity relationship study of a series of novel oxazolidinone derivatives as IL-6 signaling blockers.
Dongguk University-Seoul
Synthesis and biological evaluation of novel thieno[2,3-d]pyrimidine-based FLT3 inhibitors as anti-leukemic agents.
Yonsei University
Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1a/malate dehydrogenase 2 inhibitors.
Dongguk University-Seoul
Piperazinyl-oxadiazoles as selective sphingosine-1-phosphate receptor agonists.
Boehringer Ingelheim Pharmaceuticals
Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators.
Sk Biopharmaceuticals
Synthesis of a novel series of 2-alkylthio substituted naphthoquinones as potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors.
Dongguk University-Seoul
Discovery of a novel series of benzimidazole derivatives as diacylglycerol acyltransferase inhibitors.
Dongguk University-Seoul
Synthesis and pharmacological evaluation of carbamic acid 1-phenyl-3-(4-phenyl-piperazine-1-yl)-propyl ester derivatives as new analgesic agents.
Sk Biopharmaceuticals
Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging.
Sungkyunkwan University School of Medicine
A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.
National Cancer Institute-Frederick
Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.
National Cancer Institute-Frederick
HIF-1a inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.
Dongguk University-Seoul
A novel class of highly potent multidrug resistance reversal agents: disubstituted adamantyl derivatives.
Chung-Ang University
A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties.
Boehringer Ingelheim Pharmaceuticals
Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseases.
Korea University
Synthesis and biological evaluation of O4'-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents.
Mansoura University
Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
Yonsei University
Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta.
National Cancer Institute-Frederick
Perspective for Discovery of Small Molecule IL-6 Inhibitors through Study of Structure-Activity Relationships and Molecular Docking.
Dongguk University
Discovery of a NADPH oxidase inhibitor, (E)-3-cyclohexyl-5-(4-((2-hydroxyethyl)(methyl)amino)benzylidene)-1-methyl-2-thioxoimidazolidin-4-oneone, as a novel therapeutic for Parkinson's disease.
Korea University
2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.
Niddk
Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C).
National Cancer Institute-Frederick
Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design.
TBA
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.
Dongguk University-Seoul
Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.
Korea Research Institute of Bioscience and Biotechnology
Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.
Kribb
Creating an a7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein
Uc San Diego