The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for PR Griffin


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor.EBI
The Scripps Research Institute
Small molecule amides as potent ROR-¿ selective modulators.EBI
The Scripps Research Institute
Hydrophobic Interactions Improve Selectivity to ERa for Ben-zothiophene SERMs.EBI
TBA
Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.EBI
Emory University School of Medicine
Structure-Activity Relationship and Biological Investigation of SR18292 (EBI
The Scripps Research Institute
Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone.EBI
The Scripps Research Institute
Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ Antagonists.EBI
The Scripps Research Institute
Identification of potent RORβ modulators: Scaffold variation.EBI
The Scripps Research Institute
Identification of an aminothiazole series of RORβ modulators.EBI
The Scripps Research Institute
Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists.EBI
The Scripps Research Institute
Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics.EBI
The Scripps Research Institute
NOVEL AMINE-SUBSTITUTED PHTHALAZINES AND DERIVATIVES AS SOS1 INHIBITORSBDB
Jazz Pharmaceuticals Ireland
6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compoundsBDB
Pfizer
Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.BDB
University of Massachusetts
Methyl-pyrrolidine ether derivativesBDB
Hoffmann-La Roche
[35S]Guanosine-5'-O-(3-thio)triphosphate binding as a measure of efficacy at human recombinant dopamine D4.4 receptors: actions of antiparkinsonian and antipsychotic agents.BDB
Institut De Recherches Servier
Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.BDB
Gliatech