Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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6 articles for LJV Galietta

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Identification of 6,9-dihydro-5H-pyrrolo[3,2-h]quinazolines as a new class of F508del-CFTR correctors for the treatment of cystic fibrosis.

University of Palermo

Current development of CFTR potentiators in the last decade.

University of Palermo

Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1

D3-Pharmachemistry

An overview on chemical structures as ΔF508-CFTR correctors.

University of Palermo

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

University of Genoa

Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A).

San Francisco State University