BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 765K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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14 articles for SE Drozda

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
17
Discovery of a novel Kv7 channel opener as a treatment for epilepsy.EBI
Pfizer
21
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.EBI
Pfizer
17
An octahydro-cyclopenta[c]pyrrole series of inhibitors of the type 1 glycine transporter.EBI
Pfizer
20
 
A water soluble benzazepine cholecystokinin-B receptor antagonistEBI
TBA
6
 
N-alkyl quinuclidinium substance P antagonistsEBI
TBA
5
 
Nuclear variations of quinuclidine substance P antagonists: 2-diphenylmethyl-1-azabicyclo[3.2.2]nonan-3-aminesEBI
TBA
3
 
Preparation and radiolabelling of CP-96,345, the first non-peptide substance P antagonistEBI
TBA
19
Structure-activity relationships of potent, selective inhibitors of neuronal nitric oxide synthase based on the 6-phenyl-2-aminopyridine structure.EBI
Pfizer
2
[3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.EBI
Pfizer
27
5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists.EBI
Pfizer
16
Aza-tricyclic substance P antagonists.EBI
Pfizer
16
The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1- azabicyclo[2.2.2]-octan-3-amine as a novel, nonpeptide substance P antagonisst.EBI
Pfizer
17
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.EBI
Pfizer
24
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.EBI
Pfizer