50 articles for E Proschak
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Goethe-University Frankfurt
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor¿ Modulators.
Goethe-University Frankfurt
Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands.
Goethe-University Frankfurt
Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism.
Goethe-University Frankfurt
Molecular determinants for improved activity at PPARa: structure-activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARa.
Goethe-University Frankfurt
Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors.
Goethe University
Exploring the chemical space of multitarget ligands using aligned self-organizing maps.
Goethe University
Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.
Goethe-University Frankfurt
Synthesis and structure-activity relationship studies of novel dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase.
Goethe-University Frankfurt
Design and synthesis of dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors.
Zafes/Liff/Osf Goethe-University Frankfurt
Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screening.
Johann Wolfgang Goethe University
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
Johann Wolfgang Goethe University
Dual-target virtual screening by pharmacophore elucidation and molecular shape filtering.
TBA
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.
Zafes/Liff/Osf Goethe-University Frankfurt
Truxillic acid derivatives act as peroxisome proliferator-activated receptor gamma activators.
Goethe-University Frankfurt
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARgamma modulator.
Goethe-University Frankfurt
2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
Johann Wolfgang Goethe University
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism.
Ludwig-Maximilians-University of Munich
Development of a Potent and Selective G2A (GPR132) Agonist.
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.
Max Planck Institute of Molecular Physiology
Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells.
Goethe University Frankfurt
-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.
Goethe-University
-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.
Helmholtz Institute For Pharmaceutical Research Saarland
Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARγ Modulator.
Goethe University
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics.
Goethe University Frankfurt
Discovery of Irbesartan Derivatives as BLT2 Agonists by Virtual Screening.
Fraunhofer Institute For Translational Medicine and Phamacology Itmp
Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.
Goethe-University Frankfurt
Demonstrating Ligandability of the LC3A and LC3B Adapter Interface.
Goethe-University Frankfurt
Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase.
Goethe-University of Frankfurt
First Structure-Activity Relationship Study of Potent BLT2 Agonists as Potential Wound-Healing Promoters.
Fraunhofer Ime
Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors.
Institute For Tumor Biology and Experimental Therapy
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.
Goethe-University Frankfurt
Computer-Aided Fragment Growing Strategies to Design Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase.
Goethe-University
Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.
Goethe-University Frankfurt
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.
Goethe University Frankfurt
Polypharmacology by Design: A Medicinal Chemist's Perspective on Multitargeting Compounds.
Goethe University Frankfurt
Structure optimization of a new class of PPARγ antagonists.
Fraunhofer Institute For Molecular Biology and Applied Ecology Ime
A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode.
Goethe-University Frankfurt
Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA
Goethe University Frankfurt
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype.
Goethe-University Frankfurt
Computer-Aided Selective Optimization of Side Activities of Talinolol.
Goethe-University of Frankfurt
Vanillin-derived antiproliferative compounds influence Plk1 activity.
Johann-Wolfgang-Goethe University of Frankfurt
Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology.
Goethe University Frankfurt
DrugBank screening revealed alitretinoin and bexarotene as liver X receptor modulators.
Goethe-University Frankfurt
Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain.
University of California Davis