31 articles for R Bai
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents.
Duquesne University
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors.
Georgia State University
Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
Texas State University
Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation.
University of Padova
Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors.
University of Padova
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential.
Duquesne University
Synthesis and biological evaluation of 4'-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists.
China Pharmaceutical University
Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.
Hangzhou Normal University
Synthetically Feasible De Novo Molecular Design of Leads Based on a Reinforcement Learning Model: AI-Assisted Discovery of an Anti-IBD Lead Targeting CXCR4.
Hangzhou Normal University
Discovery of matrix metalloproteinase inhibitors as anti-skin photoaging agents.
Hangzhou Normal University
Artificial Intelligence-Assisted Optimization of Antipigmentation Tyrosinase Inhibitors: De Novo Molecular Generation Based on a Low Activity Lead Compound.
Hangzhou Normal University
Click chemistry-aided drug discovery: A retrospective and prospective outlook.
Hangzhou Normal University
Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues.
Baylor University
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation.
Zhejiang University
Synthesis of Novel Kidney-Type Glutaminase Allosteric Inhibitors Targeting the Critical Lys-320 Residue.
Zhejiang University
Medicinal chemistry updates of novel HDACs inhibitors (2020 to present).
Hangzhou Normal University
Discovery of small-molecule compounds and natural products against Parkinson's disease: Pathological mechanism and structural modification.
Zhejiang University
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).
Hangzhou Normal University
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Central South University
Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease.
China Pharmaceutical University
Hydroxypyridinone-Based Iron Chelators with Broad-Ranging Biological Activities.
Zhejiang University
Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity.
Zhejiang University
Synthesis and biological evaluation of dihydrobenzofuran lignans and related compounds as potential antitumor agents that inhibit tubulin polymerization.
University of Antwerp
Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease.
Zhejiang University
Discovery of small-molecule candidates against inflammatory bowel disease.
Zhejiang University
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents.
University of Bologna
Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates.
China Pharmaceutical University