BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for MS Wolfe

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Part 1: Notch-sparing¿-secretase inhibitors: The identification of novel naphthyl and benzofuranyl amide analogs.EBI
Harvard Medical School
Stereochemical analysis of (hydroxyethyl)urea peptidomimetic inhibitors of gamma-secretase.EBI
Harvard Medical School
Secretase targets for Alzheimer's disease: identification and therapeutic potential.EBI
Harvard Medical School
Probing pockets S2-S4' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimetics.EBI
Harvard Medical School
 
Synthesis and evaluation of 4′-5′-dehydro-5′-fluoroaristeromycins as S-adenosyl-L-homocysteine (AdoHcy) hydrolase inhibitorsEBI
TBA
Discovery of a Subnanomolar helical D-tridecapeptide inhibitor of gamma-secretase.EBI
Harvard Medical School
Design of Transmembrane Mimetic Structural Probes to Trap Different Stages of γ-Secretase-Substrate Interaction.EBI
University of Kansas
Oxidation of neplanocin A to the corresponding 3'-keto derivative by S-adenosylhomocysteine hydrolase.EBI
University of Kansas
4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase.EBI
University of Kansas