BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for AA Nagel

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.EBI
Pfizer
Design and synthesis of 1-heteroaryl-3-(1-benzyl-4-piperidinyl)propan-1-one derivatives as potent, selective acetylcholinesterase inhibitors.EBI
Pfizer
An initial three-component pharmacophore for specific serotonin-3 receptor ligands.EBI
Pfizer
Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists.EBI
Pfizer
Aromatic thiazole derivatives: structurally novel and selective serotonin-3 receptor antagonists.EBI
Pfizer
 
Novel in vitro and in vivo inhibitors of prolyl endopeptidaseEBI
TBA
Novel benzisoxazole derivatives as potent and selective inhibitors of acetylcholinesterase.EBI
Pfizer
5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety.EBI
Pfizer
1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents.EBI
Pfizer