20 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors.
University of Ljubljana
Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.
Cubist Pharmaceuticals
Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Cubist Pharmaceuticals
Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Cubist Pharmaceuticals
Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity.
University of Leeds
Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).
Astrazeneca
Computer-aided identification of novel 3,5-substituted rhodanine derivatives with activity against Staphylococcus aureus DNA gyrase.
University of The Sciences
Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents.
Astrazeneca R&D Boston
Combatting Drug-Resistant Bacteria with Gyrase and Topoisomerase IV Inhibitors: Patent Highlight.
TBA
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
Astrazeneca
Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.
Astrazeneca R&D Boston
Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens.
Shandong University
Synthesis, biological and molecular modelling for 1,3,4-thiadiazole sulfonyl thioureas: bacterial and fungal activity.
Vietnam National University
Recent advances in DNA gyrase-targeted antimicrobial agents.
Queensland University of Technology
Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Cubist Pharmaceuticals
Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus.
Birla Institute of Technology & Science-Pilani
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
University of Ljubljana
New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV.
Islamia College University
Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B.
University of Ljubljana
