BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 760K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for E Chapman

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
1
An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.EBI
University of Arizona
1
Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.EBI
University of Arizona
34
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78.EBI
University of Arizona
14
Physachenolide C is a Potent, Selective BET Inhibitor.EBI
University of Arizona
54
Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action.EBI
University of Arizona
24
Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.EBI
Indiana University School of Medicine
8
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs.EBI
Indiana University School of Medicine
58
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.EBI
Indiana University School of Medicine
8
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.EBI
University of Arizona
147
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.EBI
Indiana University School of Medicine
53
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness.EBI
Indiana University
22
GroEL/ES inhibitors as potential antibiotics.EBI
Indiana University
36
A biochemical screen for GroEL/GroES inhibitors.EBI
Indiana University
50
Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus.EBI
Indiana University School of Medicine
14
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA).EBI
Indiana University School of Medicine
2
ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A.EBI
University of Arizona