Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for JE Rowedder

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

The discovery of quinoline based single-ligand human H

Glaxosmithkline

Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain.

Glaxosmithkline

Design of Phthalazinone Amide Histamine H

Glaxosmithkline

Discovery of the first potent and selective α

University of Strathclyde

Design and Development of a Macrocyclic Series Targeting Phosphoinositide 3-Kinase δ.

Gsk Medicines Research Centre

Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of

University of Nottingham

Profile of a Highly Selective Quaternized Pyrrolidine Betaine α

Glaxosmithkline Medicines Research Centre

Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis.

Glaxosmithkline Medicines Research Centre

Structure Activity Relationships of αv Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents.

University of Nottingham

Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic α

University of Strathclyde

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinaseδ (PI3Kδ) Inhibitors.

University Park Nottingham