BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for BJ Bradbury

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Selenophene-containing inhibitors of type IIA bacterial topoisomerases.EBI
Achillion Pharmaceuticals
Functionalized congener approach for the design of novel muscarinic agents. Synthesis and pharmacological evaluation of N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl] amides.EBI
Niddk
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.EBI
Niddk
Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.EBI
Achillion Pharmaceuticals
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells.EBI
Achillion Pharmaceuticals
Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus.EBI
Achillion Pharmaceuticals
Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).EBI
Achillion Pharmaceuticals
Dual targeting of DNA gyrase and topoisomerase IV: target interactions of heteroaryl isothiazolones in Staphylococcus aureus.EBI
Achillion Pharmaceuticals
Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.EBI
Achillion Pharmaceuticals
Functionalized congener approach to muscarinic antagonists: analogues of pirenzepine.EBI
Niddk