BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Romazarit: a potential disease-modifying antirheumatic drug.EBI
Roche Products
Antiinflammatory 2,6-di-tert-butyl-4-(2-arylethenyl)phenols.EBI
Boehringer Ingelheim Pharmaceuticals
Benzimidazole derivatives with atypical antiinflammatory activity.EBI
TBA
Designed multiple ligands. An emerging drug discovery paradigm.EBI
Organon Laboratories
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.EBI
Wyeth-Ayerst Research
Imidazo[1,5-a]pyridines: a new class of thromboxane A2 synthetase inhibitors.EBI
TBA
 
1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitorEBI
TBA
Distribution of Bibenzyls, Prenyl Bibenzyls, Bis-bibenzyls, and Terpenoids in the Liverwort Genus EBI
Tokushima Bunri University
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.EBI
Tokushima Bunri University
Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors.EBI
Ciba-Geigy
Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.EBI
Vanderbilt University School of Medicine
Phenylephrine derivatives as leukotriene D4 antagonists.EBI
Wyeth Laboratories
Acetohydroxamic acids as potent, selective, orally active 5-lipoxygenase inhibitors.EBI
Wellcome Research Laboratories
Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities.EBI
Damanhour University
Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors.EBI
Boehringer Ingelheim Pharmaceuticals