BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for N Yoshimoto

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
A mixed population of antagonist and agonist binding conformers in a single crystal explains partial agonism against vitamin D receptor: active vitamin D analogues with 22R-alkyl group.EBI
Showa Pharmaceutical University
Design and characterization of a selenium-containing inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa), a zinc-containing metalloprotease.EBI
Showa Pharmaceutical University
Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands.EBI
Showa Pharmaceutical University
2-Methylene 19-nor-25-dehydro-1alpha-hydroxyvitamin D3 26,23-lactones: synthesis, biological activities and molecular basis of passive antagonism.EBI
Tokyo Medical and Dental University
22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor.EBI
Tokyo Medical and Dental University
A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.EBI
Showa Pharmaceutical University
Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.EBI
Tokyo Medical and Dental University
Vitamin D receptor: ligand recognition and allosteric network.EBI
Tokyo Medical and Dental University
Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.EBI
Riken
Identification of the Histidine Residue in Vitamin D Receptor That Covalently Binds to Electrophilic Ligands.EBI
Showa Pharmaceutical University
Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group.EBI
Showa Pharmaceutical University