BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

17 articles for IM McLay

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency.EBI
Aventis Pharma
Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimetics.EBI
Glaxosmithkline
Design and synthesis of new nonsteroidal glucocorticoid modulators through application of an"agreement docking" method.EBI
Glaxosmithkline
Discovery of a potent series of non-steroidal nona-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity.EBI
Glaxosmithkline
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating metabolic inactivation: an antedrug approach.EBI
Glaxosmithkline
Highly tractable, sub-nanomolar non-steroidal glucocorticoid receptor agonists.EBI
Glaxosmithkline
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.EBI
Glaxosmithkline
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.EBI
Glaxosmithkline
Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.EBI
Glaxosmithkline
Selective endothelin A receptor antagonists. 3. Discovery and structure-activity relationships of a series of 4-phenoxybutanoic acid derivatives.EBI
Rh£Ne-Poulenc Rorer
The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs.EBI
Glaxosmithkline
 
New non peptidic C5a receptor antagonistsEBI
TBA
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists.EBI
Medicines Research Centre
Drug rings database with web interface. A tool for identifying alternative chemical rings in lead discovery programs.EBI
Glaxosmithkline
Selective ET(A) antagonists. 5. Discovery and structure-activity relationships of phenoxyphenylacetic acid derivatives.EBI
RhôNe-Poulenc Rorer
Selective endothelin A receptor antagonists. 4. Discovery and structure-activity relationships of stilbene acid and alcohol derivatives.EBI
RhôNe-Poulenc Rorer
An algorithm-directed two-component library synthesized via solid-phase methodology yielding potent and orally bioavailable p38 MAP kinase inhibitors.EBI
Aventis Pharma