BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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6 articles for M Nakabayashi

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.EBI
Showa Pharmaceutical University
Combination of triple bond and adamantane ring on the vitamin D side chain produced partial agonists for vitamin D receptor.EBI
Rikkyo University
Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands.EBI
Showa Pharmaceutical University
A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.EBI
Showa Pharmaceutical University
Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.EBI
Tokyo Medical and Dental University
2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.EBI
Tokyo Medical and Dental University