29 articles for G De Simone
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Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.
Universita Degli Studi Di Firenze
Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.
Sapienza University of Rome
Kinetic and anion inhibition studies of aß-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis.
Istituto Di Biostrutture E Bioimmagini
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.
Istituto Di Biostrutture E Bioimmagini-Cnr
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
University of Bath
Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.
University of Naples Federico Ii
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors.
Istituto Di Biostrutture E Bioimmagini-Cnr
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.
Universita Degli Studi Di Firenze
Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates.
Universita Degli Studi Di Firenze
Discovery of a novel series of potent carbonic anhydrase inhibitors with selective affinity for μ Opioid receptor for Safer and long-lasting analgesia.
University of Florence
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors:
University of Florence
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
University of Bath
Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain.
Ege University
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.
University of Naples 'Federico Ii
Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII.
University of Messina
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms.
University of Messina
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy.
University of Florence
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.
University of Messina
Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates.
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.
University of Messina
