22 articles for R Yu
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-Abl(T315I) mutant.
Guangzhou Institutes of Biomedicine and Health
Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).
Genentech
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury.
Shandong First Medical University
Dual Antagonism of α9α10 nAChR and GABAB Receptor-Coupled CaV2.2 Channels by an Analgesic αO-Conotoxin Analogue.
Ocean University of China
Using Imidazo[2,1-
Ocean University of China and Laboratory For Marine Drugs and Bioproducts
Mechanism of Action and Structure-Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor.
Ocean University of China
Design, synthesis, and bioactivity study on Lissodendrins B derivatives as PARP1 inhibitor.
Ocean University of China
Progress in developing MNK inhibitors.
Ocean University of China and Laboratory For Marine Drugs and Bioproducts
Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion.
Ocean University of China
Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors.
Ocean University of China
Discovery of Novel Neuraminidase Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay.
Shanghai Institute of Technology
Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor.
The University of Queensland
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype.
Ocean University of China
Synthesis and biological evaluation of water-soluble derivatives of chiral gossypol as HIV fusion inhibitors targeting gp41.
Renmin Hospital of Wuhan University
Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90.
Ocean University of China
Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.
Chinese Academy of Sciences
Synthesis and HIV-1 RT inhibitory action of novel (4/6-substituted benzo[d]thiazol -2-yl)thiazolidin-4-ones. Divergence from the non-competitive inhibition mechanism.
Aristotle University of Thessaloniki
Mechanistic studies of inactivation of inducible nitric oxide synthase by amidines.
Northwestern University