BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 760K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

14 articles for RI Storer

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
19
Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.EBI
Pfizer
9
Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists.EBI
University of Cambridge
14
Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT2C) receptor agonists with exquisite functional selectivity over 5-HT2A and 5-HT2B receptors.EBI
Pfizer
39
Ion channels as therapeutic targets: a drug discovery perspective.EBI
Pfizer
15
Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence.EBI
Pfizer
22
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors.EBI
AstraZeneca
31
Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor.EBI
Astrazeneca
23
Fragment-Based Discovery of Novel Allosteric MEK1 Binders.EBI
Astrazeneca
9
Structural Basis for Targeting the Folded P-Loop Conformation of c-MET.EBI
Astrazeneca
16
Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines.EBI
Pfizer
31
Recent progress in sodium channel modulators for pain.EBI
Pfizer
14
Highly potent and selective NaEBI
Pfizer
27
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaEBI
Icagen
8
In vitro binding properties in rat brain of [3H]Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits.BDB
F. Hoffmann-La Roche