46 articles for HY Lee
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Ring-opened tetrahydro-¿-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms.
Taipei Medical University
Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R.
Korea Research Institute of Chemical Technology
2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase.
Taipei Medical University
Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteria.
Research Laboratories Ildong Pharmaceutical
N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling.
Taipei Medical University
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes.
Taipei Medical University
Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity.
Taipei Medical University
Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells.
Taipei Medical University
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.
Seoul National University
Synthesis and biological evaluation of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo.
Taipei Medical University
Synthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors.
Korea Institute of Science and Technology
A highly selective kappa-opioid receptor agonist with low addictive potential and dependence liability.
Kaist
Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase.
National Defense Medical Center
Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands.
Institute of Science and Technology
Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
Yonsei University
Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.
Korea Institute of Science & Technology (Kist)
Design, synthesis and biological evaluation of bisindole derivatives as anticancer agents against Tousled-like kinases.
Taipei Medical University
Effect of phenylurea hydroxamic acids on histone deacetylase and VEGFR-2.
Taipei Medical University
Development of tripeptidyl farnesyltransferase inhibitors.
Department of Chemistry and School of Molecular Science(Bk21)
Synthesis and biological evaluation of 2-quinolineacrylamides.
Kaohsiung Medical University
Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT
Korea Institute of Science and Technology
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.
Taipei Medical University
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase.
Taipei Medical University
Design and synthesis of N-alkylated saccharins as selective alpha-1a adrenergic receptor antagonists.
Merck
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.
Dongguk University-Seoul
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones.
Taipei Medical University
Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.
Korea Research Institute of Bioscience and Biotechnology
Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.
Kribb
Synthesis, enzymatic inhibition, and cancer cell growth inhibition of novel delta-lactam-based histone deacetylase (HDAC) inhibitors.
Korea Research Institute of Bioscience and Biotechnology
Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ.
The Scripps Research Institute
5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.
Taipei Medical University
3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity.
Taipei Medical University
(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo.
Taipei Medical University
PREPARATION METHOD OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
Haisco Pharmaceuticals
4,5,6-trisubstituted indazole derivatives, and preparation method and pharmaceutical use thereof
TBA
Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof
President and Fellows of Harvard College