13 articles for J Kong
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
10
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate.
Pfizer
27
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor.
Pfizer
4
Water mediated ligand functional group cooperativity: the contribution of a methyl group to binding affinity is enhanced by a COO(-) group through changes in the structure and thermodynamics of the hydration waters of ligand-thermolysin complexes.
The State University of New York
12
Discovery of a vorapaxar analog with increased aqueous solubility.
Merck Research Laboratories
7
Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors.
Soochow University
20
The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor.
Pfizer
26
Design and optimisation of a small-molecule TLR2/4 antagonist for anti-tumour therapy.
Tsinghua University
7
3'-Aminoadenosine-5'-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor.
Pfizer
3
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.
Dongguk University-Seoul
2
SUBSTITUTED PIPERIDINYL-METHYLPURINE PYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING DISEASES AND CONDITIONS
K36 Therapeutics
17
P-phenylenediamine derivative as potassium channel regulator and preparation method and medical application thereof
Shanghai Zhimeng Biopharma
47
Heterocyclic derivatives and their use in the treatment of neurological disorders
Novartis