BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for JH Holms

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Alpha-keto amides as inhibitors of histone deacetylase.EBI
Abbott Laboratories
Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.EBI
Abbott Laboratories
Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogues.EBI
TBA
Hydroxamic acid inhibitors of 5-lipoxygenase.EBI
TBA
 
Synthesis and evaluation of water soluble indole pyrrolothiazole paf antagonistsEBI
TBA
 
Synthesis of active metabolites of indole pyrrolothiazole paf antagonistsEBI
TBA
 
Discovery and optimization of indole pyrrolothiazole paf antagonistsEBI
TBA
 
Structure-activity relationships of the pyridazinone series of 5-lipoxygenase inhibitorsEBI
TBA
Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.EBI
Abbott Laboratories
Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770.EBI
Abbott Laboratories
Biaryl ether retrohydroxamates as potent, long-lived, orally bioavailable MMP inhibitors.EBI
Abbott Laboratories
The design, synthesis, and structure-activity relationships of a series of macrocyclic MMP inhibitors.EBI
Abbott Laboratories
Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors.EBI
Abbvie
Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.EBI
Abbott Laboratories
4-hydroxythiazole inhibitors of 5-lipoxygenase.EBI
Abbott Laboratories
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.EBI
Abbvie
InhibitorsBDB
Probiodrug