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11 articles for H Chan


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).EBI
Genentech
Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides.EBI
Syntex Research
Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists.EBI
Amgen
Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.EBI
Bristol Myers Squibb
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.EBI
Novartis Institutes For Biomedical Research
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.EBI
TBA
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.EBI
Novartis Pharmaceuticals
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.EBI
TBA
Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligandsBDB
Laboratorios Del Dr. Esteve
Imidazopyridyl compounds as aldosterone synthase inhibitorsBDB
Merck Sharp & Dohme
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetesBDB
Merck Sharpe & Dohme