BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for L Ruston

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Design of selective PI3Ka inhibitors starting from a promiscuous pan kinase scaffold.EBI
Astrazeneca
Discovery of AZD3147: a potent, selective dual inhibitor of mTORC1 and mTORC2.EBI
Astrazeneca
Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014.EBI
Astrazeneca
Discovery of 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an orally bioavailable, potent inhibitor of Akt kinases.EBI
Astrazeneca
Discovery of (2EBI
Astrazeneca
Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors.EBI
Astrazeneca
Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors.EBI
Astrazeneca
Biaryl urea derivative or salt thereof and preparation process and use for the sameBDB
Fudan University
Agent for treatment of eye diseasesBDB
Daito Chemix