17 articles for M Shimizu
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver.
Kanazawa University
Chemical and pharmaceutical studies on medicinal plants in Paraguay. Geraniin, an angiotensin-converting enzyme inhibitor from "paraparai mi," Phyllanthus niruri.
TBA
2-Methylene 19-nor-25-dehydro-1alpha-hydroxyvitamin D3 26,23-lactones: synthesis, biological activities and molecular basis of passive antagonism.
Tokyo Medical and Dental University
SAR-oriented discovery of peroxisome proliferator-activated receptor pan agonist with a 4-adamantylphenyl group as a hydrophobic tail.
University of Tokyo
A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.
Showa Pharmaceutical University
Pentagalloylglucose, A Xanthine Oxidase Inhibitor from a Paraguayan Crude Drug, "Molle-I" (Schinus terebinthifolius)
TBA
Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.
Tokyo Medical and Dental University
2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
Tokyo Medical and Dental University
Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
The University of Tokyo
Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position.
Tokyo Medical and Dental University
Vitamin D receptor: ligand recognition and allosteric network.
Tokyo Medical and Dental University
Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist.
Chugai Pharmaceutical
Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORĪ³t) inhibitor, S18-000003.
Shionogi
Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism.
Chugai Pharmaceutical
