The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

16 articles for W Chang


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
2'-deoxy-2'-a-fluoro-2'-ß-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.EBI
Pharmasset
Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation.EBI
Purdue University
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.EBI
TBA
Structure-Based Optimization of Novel Sterol 24-C-Methyltransferase Inhibitors for the Treatment of Candida albicans Infections.EBI
Shandong University
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.EBI
Merck
Design and synthesis of ether analogues as potent and selective M2 muscarinic receptor antagonists.EBI
Schering-Plough Research Institute
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors.EBI
Genentech
Discovery of Potent Orally Active Protease-Activated Receptor 1 (PAR1) Antagonists Based on Andrographolide.EBI
Shandong University
Pyridin-2(1H)one derivatives, their preparation and their use for the treatment of painBDB
Inserm (Institut National De La Sante Et De La Recherche Medicale)
Compound having PD-L1 inhibitory activity, preparation method therefor and use thereofBDB
Shanghai Ennovabio Pharmaceuticals
Imidazopyridazine and imidazopyridine compounds and uses thereofBDB
Incyte
Cyclic compound having dopamine D3 receptor antagonistic effectBDB
Shionogi
Heterocyclic compounds and uses thereofBDB
Incyte
Pyrimidine derivativeBDB
Aska Pharmaceutical
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding.BDB
Pharmacia Italia
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3.BDB
Bristol-Myers Squibb