BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for S Johnstone

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4.EBI
Amgen
Structure guided design of a series of sphingosine kinase (SphK) inhibitors.EBI
Amgen
Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.EBI
Astrazeneca
Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction.EBI
Amgen
N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.EBI
Astrazeneca
Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4.EBI
Amgen
Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective.EBI
Intellisyn Pharma
TETRAHYDROTHIENOPYRIMIDINESULFONAMIDE COMPOUNDSBDB
Modulus Discovery
Tricyclic compounds and their use as phosphodiesterase inhibitorsBDB
Pfizer
HIV protease inhibitorsBDB
Gilead Sciences
Substituted benzoimidazoles as modulators of ROR-γBDB
Vitae Pharmaceuticals
Piperazine-substituted benzothiophenes for treatment of mental disordersBDB
Otsuka Pharmaceutical
Substituted piperidine compound and use thereofBDB
Takeda Pharmaceutical
Therapeutic compounds, compositions and methods of use thereofBDB
Genentech
Tricyclic compounds for use as kinase inhibitorsBDB
FundaciÓN Centro Nacional De Investigaciones Oncologicas Carlos Iii