BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 756K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for L Hasvold

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.EBI
Abbvie
Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.EBI
Abbvie
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.EBI
Genentech
Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.EBI
Abbott Laboratories
Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.EBI
Abbott Laboratories
Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.EBI
Abbott Laboratories
Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereofBDB
North China Pharmaceutical New Drug R&D
Macrocyclic indole derivatives useful as hepatitis C virus inhibitorsBDB
Janssen Ireland
Triazole compounds as KSP inhibitorsBDB
Novartis
InhibitorsBDB
Probiodrug
5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle.BDB
University of Oslo