BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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27 articles for M Jalaie

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.EBI
Pfizer
Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators.EBI
Pfizer
Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-¿.EBI
Pfizer
Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment ofEBI
Pfizer
Discovery of a series of imidazo[4,5-b]pyridines with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-¿.EBI
Pfizer
Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.EBI
Pfizer
Benzyl ether structure-activity relationships in a series of ketopiperazine-based renin inhibitors.EBI
Pfizer
Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors.EBI
Pfizer
Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195).EBI
Pfizer
ACRYLAMIDE COMPOUNDSBDB
NRG Therapeutics
COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERSBDB
Case Western Reserve University
Amino pyrimidine derivativesBDB
Novartis
Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitorsBDB
Incyte
Substituted bridged diazepane derivatives and use thereof as TASK-1 and TASK-3 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Quinoline compounds as modulators of RAGE activity and uses thereofBDB
TBA
Inhibitors of glucocorticoid receptorBDB
Oric Pharmaceuticals
PRMT5 inhibitorsBDB
Ctxt
Conjugate comprising a neurotensin receptor ligand and use thereofBDB
3B Pharmaceuticals
Heteroaryl compounds and uses thereofBDB
Celgene Car
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDHBDB
Novartis
Lactams as inhibitors of rockBDB
Bristol-Myers Squibb
Inhibitors of SYKBDB
Hoffmann-La Roche
Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitorsBDB
Novartis
Inhibitor of bruton's tyrosine kinaseBDB
Centaurus Biopharma
Substituted cyanoguanidines as oral anti-viralsBDB
Abbvie
Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.BDB
Syracuse University
Generation of oxamic acid libraries: antimalarials and inhibitors of Plasmodium falciparum lactate dehydrogenase.BDB
University of Mississippi