67 articles for V Kumar
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
25
Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D
National Institute On Drug Abuse-Intramural Research Program
29
Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.
De Montfort University
15
6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors.
Csir-Indian Institute of Integrative Medicine
1
A chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in vitro cytotoxicity, Cdk inhibition and physicochemical properties.
India Academy of Scientific & Innovative Research (Acsir)
39
Discovery of 7-(Prolinol-N-yl)-2-phenylamino-thiazolo[5,4-d]pyrimidines as Novel Non-Nucleoside Partial Agonists for the A2A Adenosine Receptor: Prediction from Molecular Modeling.
Julius-Maximilians-Universit£T W£Rzburg
21
Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors.
Academia Sinica
16
Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.
Columbia University College of Physicians and Surgeons
29
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
National Cancer Institute-Cro
8
Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Cubist Pharmaceuticals
4
Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram.
National Institute On Drug Abuse
18
C7ß-methyl analogues of the orvinols: the discovery of kappa opioid antagonists with nociceptin/orphanin FQ peptide (NOP) receptor partial agonism and low, or zero, efficacy at mu opioid receptors.
University of Bath
19
Pyrrolo- and pyridomorphinans: non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists.
University of Bath
9
Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors.
National Institute of Pharmaceutical Education and Research
6
Novel and high affinity fluorescent ligands for the serotonin transporter based on (s)-citalopram.
National Institute On Drug Abuse-Intramural Research Program
7
Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66.
National Institute On Drug Abuse-Intramural Research Program
11
Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors.
National Institute of Pharmaceutical Education and Research
14
Selectively promiscuous opioid ligands: discovery of high affinity/low efficacy opioid ligands with substantial nociceptin opioid peptide receptor affinity.
University of Bath
1
Methoxychalcone inhibitors of androgen receptor translocation and function.
National Cancer Institute-Bethesda
16
Use of receptor chimeras to identify small molecules with high affinity for the dynorphin A binding domain of the kappa opioid receptor.
Adolor
18
2,6-Disubstituted aryl carboxylic acids, leaving groups"par excellence" for benzisothiazolone inhibitors of human leukocyte elastase.
Sterling Winthrop Pharmaceutical Research Division
25
Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.
Rochester
2
Aß-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity.
Sanofi Pharmaceuticals
11
Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.
University of Copenhagen
15
Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents.
National Institute of Pharmaceutical Education and Research (NIPER)
17
Discovery of bishomo(hetero)arylpiperazines as novel multifunctional ligands targeting dopamine D(3) and serotonin 5-HT(1A) and 5-HT(2A) receptors.
Universita Di Siena
13
Inhibitors of human leukocyte elastase. 3.1 inhibition by tetrahydrobenzisothiazolinylmethyl aryl carboxylates
TBA
15
Mannich reaction mediated derivatization of chromones and their biological evaluations as putative multipotent ligands for the treatment of Alzheimer's disease.
Central University of Punjab
7
Chemistry and pharmacological aspects of furanoid cannabinoids and related compounds: Is furanoid cannabinoids open a new dimension towards the non-psychoactive cannabinoids?
CSIR-Indian Institute of Integrative Medicine
10
Phenylstyrylpyrimidine derivatives as potential multipotent therapeutics for Alzheimer's disease.
Central University of Punjab
1
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review.
University of Kwazulu-Natal (Westville)
25
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease.
Central University of Punjab
12
Synthesis and evaluation of novel peripherally restricted kappa-opioid receptor agonists.
Adolor
2
A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center
2
Aminotriazole and Aminotetrazole Inhibitors of LSD1 as Epigenetic Modulators.
Dart Neuroscience
4
Solid phase synthesis and evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH(2)Br) ([Phe(p-bromoacetamide)(4)]TIPP), a potent affinity label for delta opioid receptors.
University of Maryland
21
Extended TIP(P) analogues as precursors for labeled delta-opioid receptor ligands.
University of Maryland
1
A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center
23
Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment.
National Institute On Drug Abuse-Intramural Research Program
18
Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D
National Institute On Drug Abuse-Intramural Research Program
22
Dipropargyl substituted diphenylpyrimidines as dual inhibitors of monoamine oxidase and acetylcholinesterase.
Central University of Punjab
1
Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship.
Csir-Indian Institute of Integrative Medicine
61
Aminoalkylindoles: structure-activity relationships of novel cannabinoid mimetics.
Sanofi Research Division
31
Novel cAMP PDE III inhibitors: imidazo[4,5-b]pyridin-2(3H)-ones and thiazolo[4,5-b]pyridin-2(3H)-ones and their analogs.
Sterling Winthrop Pharmaceuticals Research Division
13
Isolation of Flavonoids and Flavonoid Glycosides from Myrsine africana and Their Inhibitory Activities against Mushroom Tyrosinase.
University of Pretoria
22
Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D
National Institute On Drug Abuse
12
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D
National Institute On Drug Abuse-Intramural Research Program
13
Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor.
Csir-Indian Institute of Integrative Medicine
1
Synthesis, pH dependent, plasma and enzymatic stability of bergenin prodrugs for potential use against rheumatoid arthritis.
Csir-Indian Institute of Integrative Medicine
30
Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer Model.
Csir-Indian Institute of Integrative Medicine
54
CDK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS
Onquality Pharmaceuticals China
22
Modulators of the 5-hydroxytryptamine receptor 7 and their method of use
Temple University
147
Cyanopyrrolidines as dub inhibitors for the treatment of cancer
Mission Therapeutics
184
Pyrimidine tricyclic enone derivatives for inhibition of ROR-gamma and other uses
Reata Pharmaceuticals
51
Selective androgen receptor degrader (SARD) ligands and methods of use thereof
University of Tennessee Research Foundation