23 articles for JA Ellman
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease.
University of California
Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP.
Yale University
Novel inhibitors of alpha 4 beta 1 integrin receptor interactions through library synthesis and screening.
University of California
Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.
Yale University
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
University of California
Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for Chagas disease chemotherapy.
University of California
Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Yale University
General solid-phase method to prepare novel cyclic ketone inhibitors of the cysteine protease cruzain.
University of California
Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly.
University of California
Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.
University of California
Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation.
University of California
Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors.
Yale University
Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn.
Oregon Health Sciences University
Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.
University of California
Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor.
Yale University
X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.
Yale University
Substituted pyridine derivatives useful as C-FMS kinase inhibitors
Janssen Pharmaceutica
2-Thiazolylimino/heteroarylimino-5-arylidene-4-thiazolidinones as new agents with SHP-2 inhibitory action.
Aristotle University
Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1.
Korea Research Institute of Bioscience and Biotechnology