BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for G Spraggon

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-CeEBI
Genomics Institute of The Novartis Research Foundation
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.EBI
Genomics Institute of The Novartis Research Foundation
Structure-Based Design of Selective LONP1 Inhibitors for Probing EBI
Genomics Institute of The Novartis Research Foundation
Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.EBI
Genomics Institute of The Novartis Research Foundation (Gnf)
Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.EBI
Genomics Institute of The Novartis Research Foundation
Inhibitors of lysine specific demethylase-1BDB
Celgene Quanticel Research
[7,6]-fused bicyclic antidiabetic compoundsBDB
Merck Sharp & Dohme
Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.BDB
Wyeth Research
Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1.BDB
Korea Research Institute of Bioscience and Biotechnology
Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.BDB
Institut Curie