BDBM50121971 2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hydrazide::CHEMBL157428::bis(thiosalicyl)hydrazide

SMILES Sc1ccccc1C(=O)NNC(=O)c1ccccc1S

InChI Key InChIKey=BCDWFVITTFIUNV-UHFFFAOYSA-N

Data  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50121971   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataEC50:  4.30E+3nMAssay Description:Effective concentration of the compound against viral replication by Reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibitory activity of the compound against viral proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against viral attachmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postasse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against RAdT of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against rCdG of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed