BDBM14512 N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-2-oxo-6-phenyl-3-[(4-phenylbutyl)amino]-1,2-dihydropyrazin-1-yl}acetamide::Pyrazinone Analog 25d

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCCc3ccccc3)c2=O)-c2ccccc2)cc1

InChI Key InChIKey=VFCIBZCPWGCMAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14512   

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14512(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-2-ox...)
Affinity DataIC50: 7.10E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14512(N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-2-ox...)
Affinity DataIC50: 4.10E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed