BDBM102669 CHEMBL1288726::US8541572, 976

SMILES CCN1CCN(CC1)c1ccc(O)c(n1)-c1ccc(cc1F)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O

InChI Key InChIKey=NSKDLLYTWJVRPJ-JGCGQSQUSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102669   

TargetTumor necrosis factor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102669(CHEMBL1288726 | US8541572, 976)
Affinity DataKi:  0.0988nM IC50:  39.8nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM102669(CHEMBL1288726 | US8541572, 976)
Affinity DataKi:  0.100nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed