BDBM108225 2,2-dimethyl-N-phenyl-5-[6,7,8-trihydroxy-5- (hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2-a]pyridin-2- yl]pentanamide (Compound 11)

SMILES CC(C)(CCCc1cn2C(CO)C(O)C(O)C(O)c2n1)C(=O)Nc1ccccc1

InChI Key InChIKey=BJVGBJYNQFORDI-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108225   

TargetLysosomal acid glucosylceramidase(Human)
Nankai University

LigandPNGBDBM108225(2,2-dimethyl-N-phenyl-5-[6,7,8-trihydroxy-5- (hydr...)
Affinity DataKi:  18.9nMpH: 5.2Assay Description:To determine inhibition constant (Ki), substrate (7.5µL, various concentrations in Mcllvaine buffer, pH 5.2) and enzyme (12.5µL, 0.1mg/mL) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed