BDBM13064 4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(trifluoromethyl)-1H-pyrazole::SC-125

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(c(n1)C(F)(F)F)-c1ccc(F)cc1

InChI Key InChIKey=ZFOJSDBIQICCNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13064   

TargetCarbonic anhydrase 1(Human)
University of Marburg

LigandPNGBDBM13064(4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13064(4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
University of Marburg

LigandPNGBDBM13064(4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Marburg

LigandPNGBDBM13064(4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed