BDBM134290 US8853228, 155

SMILES CCc1nc(N)nc(N)c1C#CCc1cccc(c1)-c1cncnc1

InChI Key InChIKey=UEZKDWYIIOOENX-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 134290   

TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

US Patent
LigandPNGBDBM134290(US8853228, 155)
Affinity DataIC50:  35nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Connecticut

US Patent
LigandPNGBDBM134290(US8853228, 155)
Affinity DataIC50:  160nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Streptococcus pyogenes)
University Of Connecticut

US Patent
LigandPNGBDBM134290(US8853228, 155)
Affinity DataIC50:  23nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
In DepthDetails US Patent