BDBM14773 4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclohexane-1-carboxylic acid::4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid::Ariflo::Cilomilast::SB207499

SMILES COc1ccc(cc1OC2CCCC2)C3(CCC(CC3)C(=O)O)C#N

InChI Key InChIKey=CFBUZOUXXHZCFB-UHFFFAOYSA-N

Data  2 KI  11 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14773   

LigandPNGBDBM14773(Ariflo | 4-cyano-4-[3-(cyclopentyloxy)-4-methoxyph...)
Affinity DataIC50: 25nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)