BDBM154570 2-Hydroxyimino-3-phenylpropanoic acid (HIPP)

SMILES ON=C(Cc1ccccc1)C(O)=O

InChI Key InChIKey=PNTMGOUAICFJQK-NTMALXAHSA-N

Data  1 IC50  3 Kd  3 ITC

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 154570   

TargetC-terminal-binding protein 2(Homo sapiens (Human))
University of Massachusetts Medical School

LigandPNGBDBM154570(2-Hydroxyimino-3-phenylpropanoic acid (HIPP))
Affinity DataIC50:  745nMpH: 7.1Assay Description:Purified CtBP2 in 50% glycerol was added to 150 μM NADH and variable amounts of MTOB and HIPP in buffer containing 25 mM HEPES, pH 7.1, 25 mM p...More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 3 hits for monomerid = 154570   

CellC-terminal-binding protein 2 (CtBP2)(Homo sapiens (Human))
University of Massachusetts Medical School

SyringePNGBDBM154570(2-Hydroxyimino-3-phenylpropanoic acid (HIPP))
ITC DataΔG°: -7.88kcal/mole −TΔS°: 2.10kcal/mole ΔH°: -10.0kcal/mole logk: 7.59E+5
pH: 8.5 T: 20.00°C 
CellC-terminal-binding protein 1 (CtBP1)(Homo sapiens (Human))
University of Massachusetts Medical School

SyringePNGBDBM154570(2-Hydroxyimino-3-phenylpropanoic acid (HIPP))
ITC DataΔG°: -7.40kcal/mole −TΔS°: 3.85kcal/mole ΔH°: -11.4kcal/mole logk: 3.34E+5
pH: 8.5 T: 20.00°C 
CellC-terminal-binding protein 1 (CtBP1)(Homo sapiens (Human))
University of Massachusetts Medical School

SyringePNGBDBM154570(2-Hydroxyimino-3-phenylpropanoic acid (HIPP))
ITC DataΔG°: -8.60kcal/mole −TΔS°: 8.40kcal/mole ΔH°: -16.7kcal/mole logk: 2.60E+6
pH: 7.5 T: 20.00°C